It will probably break some display devices (mobile phones, PDAs etc, although I haven't found a study on this yet)
Just because your website stays open in a window doesn't mean the user will stay there. It's like thinking you are popular because you follow the popular kids around, even when they don't want you to.
So, in a nutshell, think Long and Hard before you invoke the dreaded _blank.
Exported from the old Wiblog system on 21/01/2020 21:49:23. Thanks for being a part of this.